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(2018) 97:e12070

486 Mitochondria-targeted drugs NAD supplements NADH is the raw material for superoxide production in mitochondria

Effects of NAD + precursor-based clinical interventions on the liver and isolated PBMCs Pioneering studies primarily conducted with healthy participants over short-term periods were designed to assess the dose tolerance and safety of NAD + precursors, particularly NR [76] (Table 2)

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