Airway patency was maintained, and only mild narrowing of the lumen was observed, which did not impair respiratory function
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doi: 10.1007/s00393-016-0229-5 21 GuernePACarsonDALotzM
Zileuton, an anti-inflammatory compound, inhibits LOX5 and decreases -secretase, A, and tau after three months of treatment in a 3xTg mouse AD model ( Other inhibitors APP/PS1 mice treated with the iron chelator deferoxamine demonstrate reduced A and improved memory, but no significant improvement in cognition and memory is observed in AD patients (Ross and Siegel, 2021)