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The results found that people were more likely to maintain their weight or continue losing weight early on after stopping semaglutide, but most people saw either partial or full weight regain over time

Each of these has its own side effect profile, and many are associated with metabolic changes, including weight gain, insulin resistance, and increased cardiovascular risk

In the safety outcomes trial (DEVOTE), a total of 1983 (52%) of the 3818 TRESIBA treated patients with type 2 diabetes were 65 years or older and 381 (10%) were 75 years or older