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Adverse effects by gender and age Similar proportions of men and women reported AEs across treatment groups (Fig

Alongside nausea, vomiting and constipation, clinicians are now seeing a marked increase in haemorrhoids (piles) among patients using GLP-1 medications a condition that can be painful, distressing and, in some cases, mistaken for more serious disease

Native GLP-1 has a short half-life due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) (3)

Clostridia such as CB are highly sensitive to oxygen

GLP-1 receptors are present in many tissues ranging from the brain to the heart to the retinal pigment epithelium