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Zhang and others showed GSTO2 in Apis cerana cerana had peroxidase activity toward CHP and t-butylhydroperoxide [130]
The ELF GSH levels after the rest period was the expected 250 M but when the mice were sacrificed immediately following the third day of CS exposure the ELF GSH levels were no different than control levels unlike the nave mice which CS exposure depleted the ELF GSH levels by 50% (Figure 4A)
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KD was shown to slow tumor growth in immunocompromised mice that had genetically and metabolically differentiated melanoma xenografts, indicating that it can inhibit tumor progression regardless of the genetic basis of the tumors
Notes: Chemically related to neostigmine, but has a longer duration of action and less GI effects Figure 2
