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Furthermore, the benefits of GLP-1 RA now extend to patients with peripheral artery disease (PAD) and T2DM

Specifically, liraglutide did not induce ROS or increase PTX3 (an inflammatory signal) expression in endothelial cells in one study, 69 and in fact, it attenuated the increases in both ROS and PTX3 induced by TNF- , suggesting it was not increasing inflammatory activity

A number of studies have provided indirect or circumstantial evidence for the collateral induction of autophagy and senescence 69,70,71,72

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This leads to repeat tests and wasted time