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Free GSH neutralizes ROS via a REDOX reaction in which glutathione peroxidase oxidizes free GSH into GSSG [11], thereby producing a stable oxygen species and water as a byproduct

Grx2 has close to 34% homology to Grx1 and was recently identified as the enzyme required for deglutathionylation reactions in mitochondria (Gladyshev et al., 2001

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