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176 During the 1960s, it was demonstrated that orally administered glucose promotes markedly greater pancreatic insulin secretion than that induced by intravenously administered glucose, despite the plasma glucose levels being very similar- this was termed the incretin effect

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In practice, [hydroquinone] compounded up to 8% is considered to be high and is only recommended for short periods of time, says Lesley Clark-Loeser, MD, a board-certified dermatologist in Davie, Florida

however, they are often linked to allergic conjunctivitis and may induce systemic symptoms including as weariness and hypotension [12, 18]