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After a 12-week lifestyle run-in period (including dietary recommendations and physical activity counseling), patients were randomized 2:1 to WEGOVY once weekly or placebo once weekly

doi:10.1042/0264-6021:3600001

A possible explanation for this discrepancy might be the ferroptosis inducer, which was the pharmacological inhibition of GPX4 and xCT by RSL3 and erastin, respectively, in the study by Tsoi and colleagues [122] in contrast to glutathione depletion by BSO, cystine withdrawal or Gclc knockout in my study

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