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b , SDS-PAGE immunoblot of electron transport chain proteins in isolated WAT mitochondria from Control and Bmal1-KO mice harvested at the indicated timepoints (n = 6)

The next critical step in this research involves conducting in vivo studies to confirm neuroprotective activity, for example, using established mouse models

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Dendritic cells and activated microglia transmit -synuclein fragments on MHC II to CD4 T cells, which can trigger CD8 cytotoxic responses through cross-presentation pathways [83]