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Rechler and Nissley demonstrated that IGF-II was identical to multiplication stimulating activity, a factor known to stimulate DNA synthesis in chick embryo fibroblasts (11)

It was concluded that mitogenetic radiation itself resulted from heightened metabolic activity in dividing cells which could in turn stimulate metabolism in other cells [16]

Protocol complexity: Multiple compounds increase protocol complexity, cost, and monitoring requirements

doi:10.1177/15648265100311S104

The 40s are the intersection point where prevention and correction meet making it the ideal decade to build a comprehensive anti-aging strategy