As they both work in a very similar way within the body and would interact with each other, the risk of severe side effects would also increase, which may cause serious illness
Mijit, M., Caracciolo, V., Melillo, A., Amicarelli, F
doi:10.3390/nu13041317 Li Y, Chen Y, Sun-Waterhouse D
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As a small-molecule drug, orforglipron is cheaper and simpler to manufacture than peptide-based drugs such as semaglutide