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GME, L-GalDH and leucyl amino peptidase had lower expression in tea plants, but APX, glutathione S-transferase and glutathione exhibited an opposite trend (Fig

In a mouse model, trigonelline protects against lipopolysaccharide-mediated cognitive impairment by reducing OS, inhibiting proinflammatory cytokine levels, and restoring brain-derived neurotrophic factor (BDNF) levels [66]

After all necessary data was collected for the Morris water maze test, the mice were euthanized and the brain tissue was dissected

Nanoparticle formulations of the Parkinsons drug, selegiline, resulted in 12-20 fold increases in brain concentrations in laboratory animals compared to delivering the drug orally