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While the prescribing information for GLP-1 medications does not specifically list Crohn's disease as a contraindication, the Summary of Product Characteristics (SmPC) for these medicines does advise caution in patients with gastrointestinal disease and states they are not recommended in severe gastrointestinal disease

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Ozempic (semaglutide) is a GLP-1 receptor agonist, which is a completely different class of medication

Trulicity vs Ozempic Weight Loss Results Clinical trials consistently demonstrate that Ozempic produces significantly greater weight loss than Trulicity in patients with type 2 diabetes

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