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Combined with the appetite and blood sugar effects of GLP-1 and GIP, the three together may create a stronger, synergistic effect that explains the impressive results seen in early trials

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El mecanismo de accin incluye varios efectos fisiolgicos importantes : estimulan la liberacin de insulina cuando los niveles de glucosa en sangre estn elevados, suprimen la secrecin de glucagn (una hormona que aumenta el azcar en sangre), retrasan el vaciamiento gstrico y reducen el apetito actuando sobre los centros de saciedad en el cerebro

doi: 10.1038/ajh.2012.20