In addition to fatigue, a deficiency of B12 can lead to other symptoms like pale skin, headaches, depression, gastrointestinal problems, difficulty concentrating, decreased mental function, mouth and tongue pain or inflammation, and paresthesia in your hands and feet
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Its a dual agonist that mimics both GLP-1 AND GIP (glucose-dependent insulinotropic polypeptide)
Subsequently, OsGSTL1, OsGSTL2 , and OsGSTL3 ), which were named as In2-1 proteins in rice genome database ( It has been established that all GSTs exist as dimeric proteins and have serine in the active site, however, DHARs and Lambda class GSTs are monomeric, and possess catalytic cysteine in active site (Wagner et al., 2002
But as patients began shedding significant pounds, researchers took notice