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As a vital component of innate immunity, the NLRP3 inflammasome, which is the most common inflammasome, plays a crucial role in the bodys immune response and the occurrence of UC

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In conclusion, while sperm possess natural antioxidant defense mechanisms, these defenses are limited by the unique characteristics of spermatozoa, including their reduced cytoplasmic volume, high content of PUFAs, and mitochondrial ROS production