Along with weight loss, Faubions study found that both groups of women on semaglutide drugs showed improvement in heart health measures like A1C (a marker for diabetes) and blood pressure, although the women who were also on MHT did see more significant improvement in their overall cholesterol levels
Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]
RufinatschaKRadlingerBDobnerJFolieSBonCProfanterEet al
Methods: 2627 patients were enrolled in DILIN between 4/04 and 4/24 including 1983 high causality cases scored as definite (20%), highly likely (52%) or probable (28%)
Have I spoken with my own healthcare provider about whether GLP-1 treatment is appropriate for my situation