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esculentum and Avicennia marina , respectively, was shown to confer resistance to high temperature and methyl viologen-mediated oxidative stress in transgenic L

Most preclinical evidence comes from single-peptide studies

Importantly, the restoration of tumor growth and MDSC suppressive activity in CHOP-deficient mice through IL-6 overexpression highlights CHOPs regulatory role in MDSC behavior via IL-6 production

A group at the Walter Reed Army Institute of Research (WRAIR) created prefusion-stabilized S-trimer-ferritin nanoparticles (SpFNs) , which were shown to be stable candidate immunogens that elicited potent nAb titers against SARS-CoV-2 variants and robust protection against challenge in a K18-hACE2 mouse model [128, 129] (Table 3)

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