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High-concentrate diets disrupt microbial homeostasis, leading to the intraluminal accumulation of LPS within the jejunum and ileum

Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, Arajo AC, de Souza Gonzaga HF, de Bortoli Teixeira D, de Oliveira Silva Ullmann T, Sloan KP, Sloan LA (2022) GLP-1a: Going beyond Traditional Use

Getting this detail wrong isn't just a minor slip-up

Regular follow-up appointments are an integral part of treatment, allowing for monitoring of weight, metabolic parameters, and overall wellbeing

Thats also why the fundamental nature of weight loss calories in, calories out is technically true but fickle in nature