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MATERIAL AND METHODS Animals Male Hannover NMRI mice 25-30 g b.w

Brand names: Ozempic (T2D), Wegovy (weight management + CV risk reduction), Rybelsus (oral T2D)

The expression of GLP1 receptor mRNA and protein allows the effect of GLP1 on glucose metabolism in the human hypothalamus and brainstem

For intramuscular administration as directed by a physician

195 Several systematic reviews or meta-analyses have attempted to comprehensively summarize the clinical data of GLP-1 RA in the treatment of AD or PD, but the results are still inconclusive, 196200 possibly because some clinical studies are still ongoing and require ongoing attention