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CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc- and thereby promotes tumor growth

It reflects a deeper immune imbalance involving the IL-17 and IL-23 inflammatory pathways, gut microbiome dysbiosis, genetic predisposition (HLA-B27 and related alleles), and environmental triggers including trauma, infection, and metabolic dysfunction

Gynecol Endocrinol 37:497505

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