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Various organic nanomaterials, including polymeric prodrugs and nanomicelles, provide stability and biodegradability but face challenges in clinical use because of complex synthesis
Protein metabolism remains stable, but since appetite suppression reduces overall intake, protein consumption might decrease over time, impacting muscle preservation
Matching could limit the sample size but allows pairing according to potential confounding variables
Detailed plasma pharmacokinetics and absolute oral bioavailability in rodents are still being characterized in the open literature
It can also increase side effects like nausea
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