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The Golden Rule: Take It with a Meal This is the most critical piece of advice

In this observational study, women who used HRT while taking tirzepatide: Lost nearly 19% of body weight on average Had a greater proportion achieving 20%, 25%, and even 30% total weight loss Showed improvements in heart- and metabolism-related lab measures, like blood pressure and triglycerides By contrast, women who took tirzepatide without HRT lost about 14% of their body weight on average in the same timeframe

Acknowledgments We are thankful for the comments of the anonymous reviewers, which have significantly improved the quality and clarity of our manuscript

Also important are questions that explore diabetes control, symptoms that suggest hypothyroidism, history of previous surgery and medications (Tables 4, 5)

Human StudiesWhat We Know Heres the catch: all of the research mentioned above has been done in animal models