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As a subtype of glial cells vital for retina structural support, cellular homeostasis maintenance, and blood-retina barrier preservation, its reactivation would decrease lglutamic acid uptake, which results in excitotoxicity, as well as sabotage the integrity of the blood-retina barrier, leading to ultimate retinal ganglia cell death and vision damage (Ren et al., 2020)

Designing drugs or functional foods to exploit the machinery of these nutrient-sensing mechanisms may offer a potential approach for agents to treat obesity and metabolic disease

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Patients should budget for 6-12 months of therapy to achieve optimal results, making cost-per-month calculations important for treatment planning