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Peripheral IRS activation, evidenced by increased plasma levels of TNF- receptor subtype 1, IL-6, and IL-8, is significantly correlated with atypical brain metabolism, cortical atrophy, diminished cortical gray matter, compromised integrity of white matter tracts in mood-related neural networks, and altered functional connectivity and activation patterns of cerebral circuits [1, 209]

Science 365 , 6569 (2019)

The relatively short duration and transient nature of vomiting episodes suggest that most cases resolve quickly as patients adapt to the medication or implement dietary modifications

FIGURE 8 For cellular senescence, the SA--gal staining results displayed that the number of blue positive cells was significantly increased compared with the Control group ( P 0.05) (Figures 8B,C)