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Protein intake deserves particular attentionadequate protein (1.0-1.2 g/kg body weight daily during active weight loss) supports lean muscle mass preservation, which contributes to metabolic heat production

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However, it is crucial to acknowledge that this administration may also affect the inflammatory response in BLA and non BLA brain regions or improve heroin withdrawal symptoms, potentially alleviating anxiety associated with heroin withdrawal [12,75]

Side Effect Management: For those particularly prone to nausea or other gastrointestinal issues, a more gradual or carefully adjusted titration, as guided by a healthcare provider, can make the difference between successful adherence and early discontinuation

Some patients resist this framing