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doi: 10.1016/j.ejca.2005.05.009

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[DOI] [PMC free article] [PubMed] [Google Scholar] 256.Manigault K.R., Thurston M.M

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Hypoxia is a key regulator of c-Met, as it induces the expression of the transcription factor hypoxia inducible factor 1 alfa (HIF-1)

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It has, however, also been reported that GH-induced insulin resistance precedes the increase in circulating levels of fatty acids and forearm uptake of lipid intermediates (102)

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IGF-1 Pathway Activation Growth hormone released from the pituitary stimulates production of insulin-like growth factor 1 , especially in the liver

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