Because IM injections send B12 directly into muscle, the vitamin peaks in blood within about an hour, ensuring tissues get what they need
Understanding Vitamin B12 and Folate Together Vitamin B12 and folate are closely connected nutrients that support red blood cell formation, nervous system health, DNA synthesis, and energy metabolism
However, most of these are limited to bruising and bleeding at the injection site, headache, and dizziness
Since off-label uses are generally not covered by Medicare, Marks B12 shots were not covered, and he had to pay for them out of pocket
Low levels of B12 impair DNA synthesis, which interferes with the activation of folate and, as a result, reduces the production of normal red blood cells and subsequently impairs oxygen delivery