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The application of multi-OMICS approaches are gaining acceptance in the regulatory community to provide information on a chemicals hazard and risks though their mode-of-action (MOA), however, its utility in a AOP building context are still limited

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However, Bbs5 / mice exhibited a striking increase in eWAT monocytes (Figure 3D)

27 Aldehyde Dehydrogenase The human ALDH family has 19 members, among which mitochondrial ALDH2, ALDH1B1, and cytosolic ALDH1A1 are related closely to ethanol metabolism