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Clinical trials show cholelithiasis occurs in approximately 2.5% of tirzepatide-treated patients versus 1.0% on placebo

10.1016/j.yhbeh.2012.03.018 148 VogelH.WolfS.RabasaC.Rodriguez-PachecoF.BabaeiC

Huberman Lab: short-term stress blocks hunger, but stress lasting more than four to seven days flips into hunger specifically for high-fat, high-sugar comfort foods via the glucocorticoid receptor pathway

In addition, antioxidants that protect the liver from ROS damage and lipid peroxidation may be depleted: GSH, vitamin E, vitamin C and beta-carotene were found to be reduced in the NASH setting (38, 39)

Depending on health history, monitoring may also include blood glucose, kidney function when fluid loss is a concern, diabetic retinopathy follow-up, and review of planned procedures involving anesthesia or deep sedation