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J Toxicol Sci 33(2):163173 Rashed MS, Nelson SD (1989) Characterization of glutathione conjugates of reactive metabolites of 3-hydroxyacetanilide, a nonhepatotoxic positional isomer of acetaminophen

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This decrease in disulfide formation can be ascribed to the reduction in total PDI protein levels and in the ratio of oxidized versus reduced PDI that we observed in differentiating hypoxic mutant chondrocytes (Fig