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Description

This evidence relates to the branded, FDA-reviewed formulation studied in those trials and does not establish safety, effectiveness, or equivalence for compounded formulations, which are not FDA-approved finished products and may differ in concentration, excipients, and pharmacy-specific preparation

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The SURMOUNT-5 clinical trial directly compared tirzepatide (Zepbound) to semaglutide (Wegovy) over 72 weeks at their maximum tolerated doses

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This means complications such as: Neuropathy Nephropathy / CKD Retinopathy Peripheral angiopathy Foot ulcers Osteomyelitis Cataracts can be coded as diabetic complications when they appear under with in the index even if the provider doesnt explicitly write due to diabetes. For RA Coding Purposes This guideline helps ensure: More accurate HCC capture Fewer missed diabetic complication codes Better reflection of patient complexity Stronger alignment with clinical reality But (and this is where coder judgment matters) the presumption only applies when documentation does not contradict it

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