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Insulin resistance (IR), commonly associated with obesity, disrupts these processes

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Use With Caution in Research Contexts Because Retatrutide interacts with GLP-1, GIP, and glucagon receptor pathways involved in metabolism, appetite regulation, gastric-emptying pathways, and glucose signaling, additional caution may be warranted in research models involving significant metabolic, gastrointestinal, pancreatic, or cardiometabolic conditions