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These effects could potentially mitigate age-related cardiac decline and support overall heart health, though further studies are needed to confirm these benefits in humans

Ethics statement The studies involving human participants were reviewed and approved by 2021-KY-0202-002, Ethics Committee of the First Affiliated Hospital of Zhengzhou University

This integrated approach has the potential to offer synergistic effects, improving therapeutic outcomes and providing a more holistic treatment strategy for patients

In research settings, it is examined as an isolated pentadecapeptide with consistent physicochemical characteristics, which supports its use across biochemical, cellular, and preclinical experimental platforms

Documented internal abnormalities include: CNS abnormalities (including cerebral abnormalities, cerebellar malformation, hydrocephalus, microcephaly, cranial nerve deficit)