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It depends on the ambient temperature and the specific formulation

Furthermore, these pathways have also been linked to appetite regulation, modulation of gastric emptying, and cardiovascular effects (23, 24)

GLP-1R has been densely found in the choroid plexus, suggesting the possibility it may play a role in sodium transport and cerebrospinal fluid (CSF) production [102]

Additionally, the medication slows gastric emptying, which prolongs the sensation of fullness after meals and reduces appetite through effects on brain regions that regulate hunger and satiety