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1-carboxyphenyalanine is reported to be associated with poor response to metformin (Naja et al., 2023) and with lower microbiome diversity (Wilmanski et al., 2019), and previously shown to be most discriminating metabolite of insulin resistance (Diboun et al., 2021)

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[DOI] [PubMed] [Google Scholar] 37.Worthen R.J., Garzon Zighelboim S.S., Torres Jaramillo C.S., Beurel E