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Leukotoxin (Leukothera(R)) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway

(Center) In macrophages, GLP-1 can significantly increase the expression of GLP-1 receptor through G protein-coupled receptor 119 (GPR119), enhance the activity of ABCA1, lead to the increase of apo AI, and thus promote intracellular cholesterol outflow

These two pathways have overlapping functions, but insulin is mainly involved in the regulation of metabolism, and the Growth Hormone/IGF-1 pathway plays an important role in the processes of growth, development and possibly life expectancy

Shang et al[16]

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