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With consistent use of the Glutathione Injectable Pen or Glutathione IV Drip, many people notice the following improvements within 8 to 12 weeks: Skin appears plumper and more hydrated Fine lines around the eyes and mouth become less noticeable Dullness fades and the skin reflects light better This is why many of our HueBeautyGlam clients in their late 30s and 40s pair Glutathione with Vitamin B12 injections as part of their anti-aging routine