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The most commonly reported side effects are mild and transient: injection site redness or minor bruising, transient fatigue in the first one to two weeks, and occasionally mild headache following the first few injections, a pattern sometimes attributed to the acute shift in cellular energy metabolism as AMPK pathways are upregulated [3]

Fetal hemoglobin has a high oxygen affinity that facilitates increased oxygen supply in the intrauterine environment [89]

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Deferiprone and desferrioxamine combined chelation could improve puberty of adolescent males with -thalassemia major with preserved pituitary and testicular function

J.Perez-CataldoG.CastellJ