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While these drugs may help people on their journey, it is important to understand the potential for unwanted side effects when using them

Theyve also shown to improve medication compliance and may allow for reductions in medication dose, she says

If your 15 mg dose provides sustained appetite control and acceptable side effects, your healthcare provider may recommend continuing it as maintenance therapy to prevent weight regain

In May 2026, Lilly reported that its pivotal Phase 3 TRIUMPH-1 trial gave an average weight loss of about 28% to 30% on the top dose

Crossing barriers from blood-to-brain and academia-to-industry