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Olanow CW, Rascol O, Hauser R, et al

Additionally, as SOD/catalase mimetics are low-molecular weight compounds, they can enter cells more easily than their natural counterparts (Halliwell and Gutteridge, 2015)

Rather than viewing receptor activation as a binary event, biased agonism allows selective amplification of therapeutically desirable signaling while minimizing pathways associated with adverse effects (Wootten et al., 2018)