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The paper also found that cancer cell lines showed a different response, appearing to rely more on an alternative lengthening of telomeres (ALT) mechanism rather than telomerase activation directly

Mitochondrial sirtuin 3 (SIRT3) is a major modulator of mitochondrial metabolism and homeostasis, regulating UPR mt , mitochondrial biogenesis, mitophagy, fusion/fission, and antioxidant expression 98

doi: 10.1021/jf502990n

Evaluation of vitamin D levels in allergic and non-allergic asthma