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As a dermatologist, I often get questions from people who are concerned about skin changes

Additionally, an increase in the CD4+/CD8+ ratio among FM + NCWS patients after a gluten-free diet was observed, as well as a reduction in IL-17 and IL-22 levels

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The active alkylating component, phosphoramide mustard, forms alkyl adducts with DNA through a phosphoramide aziridinium intermediate, while DNA alkylation induces a damage leading to cell death (Juster-switlyk et al., 2017)

Downregulation of PPG mRNA levels by chronic GLP-1RA administration and food restriction in rats (8) further substantiates these findings