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Association of joint inflammation with pain sensitization in knee osteoarthritis: The multicenter osteoarthritis study

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It doesn't address the underlying energy deficit driving it

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Groups 1, 2, and 3 received 0.9% normal saline (0.5 mL/200 g, i.p.), mildronate (MD, 200 mg/kg/day, i.p.), and l-carnitine (CARN, 200 mg/kg/day, i.p.) for 10 uninterrupted days, respectively