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It also regulates matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), ensuring controlled tissue remodeling and balanced extracellular matrix turnover[1]

Current NICE guidance (NG49) emphasises lifestyle modification as the primary treatment for NAFLD, including weight loss, dietary changes, and increased physical activity

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For anxiety and depression that co-occur with diabetes and obesity, semaglutide and, to a lesser extent, liraglutide might be useful dually effective therapeutic options, wrote the authors from University of Eastern Finland, Karolinska Institutet in Stockholm and Griffith University in Australia

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