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The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)

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Thus, there are some issues that still need to be addressed in order to improve the preventive and therapeutic outcomes in PIPN

On the texture front, gluconolactone (a gentle polyhydroxy acid often found in Korean formulas that loosens dead skin while also acting as a humectant, adds Dr

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