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A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohns disease

Later on, the FDA approved two other brands with similar formulations to treat obesity and excess weight: Wegovy and Zepbound

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A cross-sectional analysis found that MeDi adherence was associated with increased gut microbial diversity and higher levels of short-chain fatty acids, metabolites linked to reduced inflammation and improved vascular health (De Filippis et al., 2016)