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however, the effect of OA on GLP-1 and PYY release was significantly attenuated in cells transfected with TGR5 siRNA compared to cells transfected with control siRNA (78 10% inhibition in GLP-1 release and 88 12% inhibition in PYY release) (Figure 2)

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These processes are examined in terms of receptor activation and intracellular biochemical responses rather than outcome-based effects

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This is a method used in resistance training to increase the neuromuscular demand over time