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Furthermore, concerns regarding the accumulation of Ag NPs in major organs (e.g., liver, spleen, and kidneys), the generation of reactive oxygen species (ROS), and potential genotoxic effects have led regulatory agencies such as the FDA and EMA to advocate for more stringent standardization protocols and comprehensive toxicity profiling to ensure safety and reproducibility [244]

Subcellular distribution and nrf2/keap1-interacting properties of glutathione S-transferase P in hepatocellular carcinoma

Significantly reduced serum TNF- levels relative to the TNBS model group

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A reduced intake of vitamin C, specifically less than 70 mg per day, was significantly correlated with an elevated risk of developing GDM